Fall & Spring 2009-2010 Poster Sessions/Tentative Class Dates Fall Lab Rotation 2009 Begin: August 31st End: November 16th Poster Session: November 17th & November 18th Winter Lab Rotation 2009 Begin: November 19th End: February 3rd Poster Session: February 4th & February 5th Spring Lab Rotation 2010 Begin: February 8th End: April 26th Poster Session: April 27th & 28th Tentative Class Dates CMB I - Biomolecules Coursemaster: Dr. Tim Townes/Dr. Kirill Popov Course Begins: 08/19/09 Course Ends: 10/02/09 CMB II - Genes Coursemaster: Dr. Michael Niederweis/Dr. Sunnie Thompson  Course Begins: 10/05/09 Course Ends: 11/16/09 CMB III - Cells Coursemaster: Dr. Casey Morrow Course Begins: 11/19/09 Course Ends: 12/18/09 CMB IV - Module 1 Course Begins: 01/04/10 Course Ends: 01/29/10 Bacterial Genetics & Physiology, CMB 741---(Dr. Janet Yother) Monday - Friday 8:00 am - 10:00 am BBRB 263 Cell Signaling, CMB 742---(Dr. Michael Miller) Monday - Friday 8:00 am - 10:00 am BBRB 170 CMB V - Module 2 Course Begins: 02/01/10 Course Ends: 02/26/10 Cellular & Molecular Neuroscience, CMB 754 --- (Dr. Vladimir Parpura) Monday - Friday 8:00 am - 10:00 am in SHEL 1015 Textbook: Principles of Neural Science, 4th Edition; Kandel, Schwartz, Jessell; McGraw Hill; 2000. This course will cover fundamental principles of cellular neurobiology, including membrane permeability, the ionic basis of the resting membrane potential and of the action potential, neurotransmitter substances and their receptors, synaptic transmission and plasticity and their role in learning and memory, intracellular signaling, and the role of glial cells in neuronal function. Lecturers are faculty members of the Departments of Neurobiology, Cell Biology, and Physiology & Biophysics. The course will have 5 days of lectures per week (Mon - Fri), one journal club-style discussion of a research paper, and two review sessions before the exams. Successful completion will depend on the grade in two exams (essay-style), class participation (e.g. on article discussion), and attendance. Cell & Molec. Aspects of Dev. Bio., CMB 755---(Dr. Brad Yoder) Monday, Wednesday, Friday 9:00 am - 11:00 am in MCLM 601 Virology, CMB 756---(Dr. Peter Prevelige) Monday - Friday 8:00 am - 10:00 am in BBRB 263 Text: No text required for this course.   CMB VI - Module 3 Course Begins: 03/01/10 Course Ends: 03/26/10 Eukaryotic Genetics, CMB 761---(Dr. Peter Detloff) Monday - Friday 9:00 am - 11:00 am in KAUL 437 Immunology, CMB 762---(Dr. Burrows/Barnum) Monday - Friday 8:00 am - 10:00 am in BBRB 170 Immunology is a team-taught survey course that covers basic concepts of innate and adaptive immunity. Students actively participate in the course through weekly presentations of selected immunology topics based on the current literature. This course provides an excellent foundation in immunology not only for the budding immunologist, but those in microbiology, medicine, neuroscience and other disciplines. Developmental Neuroscience, CMB 763---(Dr. Kent Keyser/Dr. Rita Cowell) Monday - Friday 8:30 am - 10:00 am in BBRB 263 Cell Matrix Interactions in Disease, CMB 765---(Dr. Anne Woods) Monday - Friday 8:00 am - 10:00 am in THT 936 This course will cover a combination of basic mechanisms underlying extracellular matrix interactions with cells, and how these go wrong in several disease processes. It will be a series of seminars, followed in the final week with oral student presentations on the disease of their choice and submission of a one-page summary. **Spring Break: 03/30/09 - 04/03/09** CMB VII - Module 4 Course Begins: 04/05/10 Course Ends: 04/30/10 Bacterial Pathogenesis, CMB 771---(Dr. David Briles) Monday, Wednesday, Friday 8:00 am -10:00 am in BBRB 170 The course in Bacterial Pathogenesis to be taught each year during fourth CMB module has been designed to be relatively comprehensive, although there is no specific text for the course.  However, there is an online (Free!!!) text called Todar's Online Textbook of Bacteriology that will serve as a good reference.  The URL for this is http://textbookofbacteriology.net/index.html. Each week students will be given a quiz based on the lectures of the preceding week.  To answer the questions, an understanding of the lecture material will be needed, but the questions are designed to stimulate thinking on the part of the students. These tests will be given not so much to evaluate the students but to help them began to think about hypotheses and concepts in this field. The final grade in the course will be based on these quizzes, the student participation in discussions.   Regular attendance will be required.   In some cases students will be allowed to take this course as an advance course.  Such students will be asked to give one of the class lectures in order to receive advanced course credit.    Diseases of The Nervous System, CMB 772---(Dr. Harry Sontheimer) Course Director: Harald Sontheimer, Ph.D; course meets Monday, Wednesday & Friday from 8:00 am-10:00 a.m in CIRC 235, Dept. Neurobiology Conference room unless specified otherwise. Overall Course Description: Major advances have been made in understanding diseases of the nervous system at a cellular and molecular level. Several new findings have had direct therapeutic implications and have resulted in the development of novel drugs or new disease management strategies. This course intends to review the most common brain and CNS disorders. Course Format: The course is a problem-based small group session that will be largely taught by students. Several UAB professors who have active research programs directed at studying nervous system diseases will be available to coach students and help them prepare lectures. Each meeting will cover one disease area. The first hour will be a formal lecture presented by 1 or 2 students and will introduce the clinical presentation of the disease, its etiology, epidemiology, and current treatment strategies. This lecture will then introduce advances made in the cellular and molecular biology of the disease. In the 2nd hour, one or two students will lead the discussion of a seminal research paper that has led to a conceptual breakthrough in our understanding of the disease. Each presentation will conclude with an open discussion and critique of the presentation by the entire group. Limitations and Course Requirements: The course is designed for graduate and medical students. The course is limited to 24 participants; for-credit participation is required; it is advantageous albeit not necessary to have successfully completed: Cellular and Molecular Neuroscience, CMB-5 (NBL 751) or Medical Neuroscience NBL 711. Test and Grading: Attendance of at least 8/10 sessions and active course participation required. A letter grade will be assigned based on: (1) 2 presentations by each student of which one will be an introductory lecture and one will be the presentation and discussion of a research paper. The quality of audiovisual material and the quality of the presentation will be judged separately. These two presentations account for 2/3 of the final grade (1/3 each). The remaining 1/3 will be based on class participation, i.e. discussions, problem solving etc, as judged by the course director. Stem Cell Biology, CMB 774---(Dr. Tom Ryan) Monday - Friday 8:00 am - 10:00 am in BBRB 263 Stem Cell Biology (CMB 774) will explore the derivation, manipulation, and differentiation of embryonic, fetal, and adult stem cells in both mice and humans. Topics to be discussed include stem cell self-renewal, teratoma formation, hematopoietic stem cells, neural stem cells, trans-differentiation, nuclear transfer, and reproductive and therapeutic cloning. The course will be a mixture of instructor lectures and interactive journal club style presentations from the current stem cell literature by the students. Students will be evaluated based upon their journal article presentations, participation in class discussions, quizzes, and attendance. Lymphocyte Biology, CMB 775---(Dr. Allan Zajac) Monday, Wednesday, Friday 8:00 am -10:00 am in BBRB 254 The objective of this class is to provide first year graduate students with the opportunity to gain a more in depth understanding of selected aspects of lymphocyte biology. Tentative topics to be cover include T cell subsets, B cell biology, lymphocyte activation and transplantation immunology. The course is literature intense and students are required to read and present numerous scientific papers. Glial Biology in Medicine, CMB 770 --- (Dr. Michael Brener) (details to be posted soon) This course will cover the role of glia in the normal development and function of the nervous system, and their role in injury and disease.  Presentations will be student led, with the assistance of the faculty. CMB VIII - Laboratory Rotation Laboratory Rotation-2hrs Laboratory Rotation-3hrs Special Courses: 1hr Laboratory Methods---(Dr. Scott Wilson) Methods and Logic ---(Dr. Chris Klug)